Svenja Morsbach, Grazia Gonella, Volker Mailänder, Seraphine Wegner, Si Wu, Tobias Weidner, Rüdiger Berger, Kaloian Koynov, Doris Vollmer, Noemí Encinas, Seah Ling Kuan, Tristan Bereau, Kurt Kremer, Tanja Weil, Mischa Bonn, Hans-Jürgen Butt, Katharina Landfester, Angewandte Chemie International Edition (2018)

Review on characterizing proteins at interfaces

Once materials come into contact with a biological fluid containing proteins, proteins are generally—whether desired or not—attracted by the material’s surface and adsorb onto it. The aim of this Review is to give an overview of the most commonly used characterization methods employed to gain a better understanding of the adsorption processes on either planar or curved surfaces. We continue to illustrate the benefit of combining different methods to different surface geometries of the material. The thus obtained insight ideally paves the way for engineering functional materials that interact with proteins in a predetermined manner.